Do short acting beta 2 agonists increase or decrease intraocular pressure?

Do short acting beta 2 agonists increase or decrease intraocular pressure?

• A. Increase
• B. Decrease
• C. No change
• D. Fluctuation

Answer: (A)

Activation of beta-2 receptors in the eye, especially on the ciliary epithelium, increases aqueous humor production by boosting fluid secretion. Short-acting beta-2 agonists can reach the eye and stimulate these receptors, leading to more aqueous humor being formed and a rise in intraocular pressure. In contrast, other agents that decrease production or increase outflow lower IOP. So the expected effect is an increase in intraocular pressure.

Activation of beta-2 receptors in the eye, especially on the ciliary epithelium, increases aqueous humor production by boosting fluid secretion. Short-acting beta-2 agonists can reach the eye and stimulate these receptors, leading to more aqueous humor being formed and a rise in intraocular pressure. In contrast, other agents that decrease production or increase outflow lower IOP. So the expected effect is an increase in intraocular pressure.